›› 1993, Vol. 13 ›› Issue (4): 200-202.

Special Issue: 实验动物资源开发与利用

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Study on Superovulation in Inbred Strain Mice

  

  1. Laboratory Animal Center,Academy of Military Medical Sciences,Beijing 100071
  • Received:1993-07-25 Online:1993-01-25 Published:2013-03-21

Abstract: Super ovulation in inbred mice can provide a lot of embryos for the establishment of mouse embryo cryobank.Pregnant mare serum gonadotropin and human chorionic gonadotropin were used for the superovulation in BALB/c and C 57 BL/6 A mice, satisfactory results were obtained by the addition of more than 1 μg of 15-methyl prostaglandin F according to the characteristics of the mouse strains. The results show that the average usable embryos obtained from one superovulated BALB/c and C57BL/6 A mouse are 22 and 23 respectively, but only 7 and 8 in control animals. The pregnancy rate is higher in the treated mice than the controls.

Key words: Inbredsnmice, Hormone, Superovulation