Laboratory Animal and Comparative Medicine

Practice in Validity Period Management of Disinfectants, Feed, and Bedding in Laboratory Animal Facilities under Good Laboratory Practice Management System

MA Wenjing, LIU Yanping, LI Yifan, GUO Huan, XIE Lihui, DU Longji, MA Jiali, WANG Hongping, LI Jiamin

Laboratory Animal and Comparative Medicine, 2026, 46(4): 593-603. DOI: 10.12300/j.issn.1674-5817.2025.162

消毒剂 Disinfectants	存放周期 Storage period	反应管作用后残存活菌浓度/（CFU·mL^-1） Viable bacterial concentration in reaction tubes after exposure/(CFU·mL^-1)	实测杀灭对数值 Measured log reduction value	可接受标准 Acceptable standards	是否合格 Qualified
0.04%次氯酸钠溶液 0.04% Sodium hypochlorite solution	消毒剂存放第0天	25.000	6.300	杀灭对数值≥5.000	合格
0.04%次氯酸钠溶液 0.04% Sodium hypochlorite solution	消毒剂存放第7天	55.000	5.930	杀灭对数值≥5.000	合格
0.1%癸甲溴铵溶液 0.1% Didecyldimethylammonium bromide solution	消毒剂存放第0天	10.000	6.700	杀灭对数值≥5.000	合格
0.1%癸甲溴铵溶液 0.1% Didecyldimethylammonium bromide solution	消毒剂存放第7天	60.000	5.890	杀灭对数值≥5.000	合格
0.2%苯扎溴铵溶液 0.2% Benzalkonium bromide solution	消毒剂存放第0天	40.000	6.100	杀灭对数值≥5.000	合格
0.2%苯扎溴铵溶液 0.2% Benzalkonium bromide solution	消毒剂存放第7天	80.000	5.770	杀灭对数值≥5.000	合格
阳性对照 Positive control	消毒剂存放第0天	5.000×10⁷	—		—
阳性对照 Positive control	消毒剂存放第7天	4.700×10⁷	—		—

Table 1 Efficacy results of different disinfectants on day 0 and day 7 after preparation

Other figure/table from this article