Laboratory animal is one of the important basic scientific research conditions to support the science and technology innovation in the fields of life science and biomedicine. The new and rapid development trend of scientific and technological innovation in China calls for strengthening the strategic position of laboratory animal resources, accurately grasping the creation mode of laboratory animal resources, further improving the policy system and operation mechanism conducive to the creation and development of laboratory animal resources, as well as the service platform for the preservation and sharing of laboratory animal resources, aiming to improve the service level of laboratory animal resources for national scientific and technological innovation.

By reviewing the development from human genome project to precision medicine, we can have a more comprehensive and accurate understanding on comparative medicine, thus provide important enlightenment for more precise and efficient comparative medicine research. Starting from the development from human genome project to precision medicine, this paper summarized and analyzed the development trend of comparative medicine, that is, humanization of laboratory animals and personification of animal models. Moreover, the paper pointed out that under the challenge of big data era, comparative medicine research should play its “cross convergence” characteristics, achieve breakthroughs in research methods and technologies, and improve the efficiency and quality of human health research.

基于有关文献和实验动物科学研究现状,阐述我国比较医学研究工作的开创、比较医学学科的建立与发展,使国内同行和广大读者了解我国比较医学的发展过程,以及比较医学的发展对现代医学和人类健康的重要意义,也对随着生命科学的迅猛发展并取得一系列突破性进展的同时出现的新问题而赋予比较医学研究的发展方向进行展望。

实验动物是生命科学研究和生物医药研发的载体,生命科学和生物医药产业的发展也极大地推动了实验动物行业的快速发展。“十三五”国家科技创新发展规划也对实验动物提出了新的发展方向和任务,如何稳步有序发展实验动物产业值得深入探讨。尽快修订并发布《实验动物管理条例》,加大对实验动物科技工作的支持,发挥各级学会、协会和联盟的作用,加强合作,破解难题,抓住机遇,对于促进实验动物产业化发展具有重要意义。

阐述和分析我国实验动物质量监测网络建设及现存问题， 针对检测市场开放而带来的国内、外检测资源之间竞争加剧这一新形势， 提出我国实验动物质量监测网络发展的主要方向和对策。

简述了浙江省10年来探索以多种形式发展实验动物科技事业的经验，包括：省计经委、省科委和省卫生厅共同投资新建省实验动物中心，使之成为实验动物商品化生产供应和动物实验社会化服务的主要基地；金华地区16个医药卫生企事业单位联合创建金华市实验动物中心，推动了该地区实验动物工作，为我省实验动物科技事业发展开辟了一条新路；采用股份制形式建设温州市实验动物中心，既有社会效益又兼顾经济效益的提高，6年的实践证明，采用股份制形式创办实验动物中心是现阶段发展实验动物科技事业的可行道路。