Laboratory Animal and Comparative Medicine ›› 2012, Vol. 32 ›› Issue (3): 250-253.DOI: 10.3969/j.issn.1674-5817.2012.03.018
Previous Articles Next Articles
ZENG Ben-hua, WEI Hong
Received:
2011-11-16
Online:
2012-06-25
Published:
2012-06-25
CLC Number:
ZENG Ben-hua, WEI Hong. Application of Germ Free Animals in Study of Human Health and Disease[J]. Laboratory Animal and Comparative Medicine, 2012, 32(3): 250-253.
[1] Travnicek J, Mandel L.Gnotobiotic techniques[J]. Folia Microbiol (Praha), 1979, 24(1):6-10. [2] Inzunza J, Midtvedt T, Fartoo M, et al.Germfree status of mice obtained by embryo transfer in an isolator environment[J]. Lab Anim, 2005, 39(4):421-427. [3] Faith JJ, Rey FE, O'Donnell D, et al. Creating and characterizing communities of human gut microbes in gnotobiotic mice[J]. ISME J, 2010, 4(9):1094-1098. [4] Falk PG, Hooper LV, Midtvedt T, et al.Creating and maintaining the gastrointestinal ecosystem: what we know and need to know from gnotobiology[J]. Microbiol Mol Biol Rev, 1998, 62(4):1157-1170. [5] Lederberg J.Infectious history[J]. Science (80-), 2000,288(5456):287-293. [6] Li M, Wang B, Zhang M, Rantalainen M, et al.Symbiotic gut microbes modulate human metabolic phenotypes[J]. Proc Natl Acad Sci U S A, 2008, 105(6):2117-2122. [7] Guarner F, Malagelada JR.Gut flora in health and disease[J]. Lancet, 2003,361(9371):512-519. [8] Backhed F, Manchester JK, Semenkovich CF, et al.Mechanisms underlying the resistance to diet-induced obesity in germ-free mice[J]. Proc Natl Acad Sci U S A, 2007, 104(3):979-984. [9] Sudo N, Chida Y, Aiba Y, et al.Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice[J]. J Physiol, 2004, 558(1):263-275. [10] Preidis GA, Versalovic J.Targeting the human microbiome with antibiotics, probiotics, and prebiotics: gastroenterology enters the metagenomics era[J]. Gastroenterology, 2009,136(6):2015-2031. [11] Inzunza J, Midtvedt T, Fartoo M, et al.Germfree status of mice obtained by embryo transfer in an isolator environment[J]. Lab Anim, 2005,39(4):421-427. [12] Hirayama K, Itoh K.Human flora-associated (HFA) animals as a model for studying the role of intestinal flora in human health and disease[J]. Curr Issues Intest Microbiol, 2005, 6(2):69-75. [13] Silley P.Human flora-associated rodents ?does the data support the assumptions?[J]. Microb Biotechnol, 2009, 2(1):6-14. [14] Che C, Pang X, Hua X, et al.Effects of human fecal flora on intestinal morphology and mucosal immunity in human flora-associated piglet[J]. Scand J Immunol, 2009, 69(3):223-233. [15] Pang X, Hua X, Yang Q, et al.Inter-species transplantation of gut microbiota from human to pigs[J]. ISME J, 2007, 1(2):156-162. [16] Lofgren JL, Whary MT, Ge Z, et al.Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia[J]. Gastroenterology, 2011, 140(1):210-220. [17] Denou E, Rezzonico E, Panoff JM, et al.A Mesocosm of Lactobacillus johnsonii, Bifidobacterium longum, and Escherichia coli in the mouse gut[J]. DNA Cell Biol, 2009, 28(8):413-422. [18] Duncan BB, Schmidt MI, Pankow JS, et al.Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study[J]. Diabetes, 2003, 52(7):1799-1805. [19] Visser M, Bouter LM, McQuillan GM, et al. Elevated C-reactive protein levels in overweight and obese adults[J]. JAMA, 1999, 282(22):2131-2135. [20] Hotamisligil GS, Shargill NS, Spiegelman BM.Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance[J]. Science (80-), 1993, 259(5091):87-91. [21] Cani PD, Amar J, Iglesias MA, et al.Metabolic endotoxemia initiates obesity and insulin resistance[J]. Diabetes, 2007, 56(7):1761-1772. [22] Cani PD, Neyrinck AM, Fava F, et al.Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia[J]. Diabetologia, 2007, 50(11):2374-2383. [23] Toda T, Saito N, Ikarashi N, et al.Intestinal flora induces the expression of Cyp3a in the mouse liver[J]. Xenobiotica, 2009,39(4):323-334. [24] Toda T, Ohi K, Kudo T, et al.Antibiotics suppress Cyp3a in the mouse liver by reducing lithocholic acid-producing intestinal flora[J]. Yakugaku Zasshi, 2009, 129(5):601-608. |
[1] | Ya ZHAO, Caiqin ZHANG, Han MENG, Jing QIN, Bing BAI, Yong ZHAO, Xu GE, Changhong SHI. Exploration of Laboratory Animal Science Teaching Practice from Perspectives of Curriculum Ideology and Politics [J]. Laboratory Animal and Comparative Medicine, 2023, 43(6): 641-646. |
[2] | Xin LIU, Shaobo SHI, Cui ZHANG, Bo YANG, Chuan QU. Construction and Evaluation of End-to-side Anastomosis Model of Autologous Arteriovenous Fistula in Mice [J]. Laboratory Animal and Comparative Medicine, 2023, 43(6): 595-603. |
[3] | Yongqiang NIE, Zhaoxia WANG. Rescue Technology and Its Application of Endangered Gene-Edited Mice [J]. Laboratory Animal and Comparative Medicine, 2023, 43(6): 636-640. |
[4] | Yong ZHAO. Evolution and Prospects of Laboratory Animal Management: A Case Study of Shanghai's Development in the Past Decade [J]. Laboratory Animal and Comparative Medicine, 2023, 43(5): 492-503. |
[5] | Liping FENG, Qi ZHU, Jinxing LIN. Current Status and Reflection on the Study of Welfare for Laboratory Fish [J]. Laboratory Animal and Comparative Medicine, 2023, 43(5): 524-530. |
[6] | Jinxing LIN, Xindong WANG, Xuebing BAI, Liping FENG, Shuwu XIE, Qiusheng CHEN. Fine Structure of the Trunk Kidney and Distribution of Its Secreted Exosomes in the Adult Zebrafish [J]. Laboratory Animal and Comparative Medicine, 2023, 43(5): 531-540. |
[7] | Liya ZHAO, Liju NI, Caiqin ZHANG, Jianping TANG, Yangzheng YAO, Yanyan NIE, Xiaoxue GU, Ying ZHAO. Establishing a Genetic Detection Protocol of Single Nucleotide Polymorphisms Panels in Inbred Rats Based on Multiplex PCR-LDR [J]. Laboratory Animal and Comparative Medicine, 2023, 43(5): 548-558. |
[8] | Shuzhen ZHANG, Yanguang ZHAO. Investigation Report on the Production and Utilization Status of Experimental Mini-pigs [J]. Laboratory Animal and Comparative Medicine, 2023, 43(5): 559-565. |
[9] | Lingzhi YU, Jianyun XIE, Liping FENG, Xiaofeng WEI. Establishment of Fluorescence qPCR Method for Detection of Staphylococcus Aureus and Its Application in Feces Detection of Rats and Mice [J]. Laboratory Animal and Comparative Medicine, 2023, 43(5): 566-573. |
[10] | Chengji WANG, Jue WANG, Haijie WANG, Weisheng LU, Yan SHI, Zhengye GU, Mingqiu WAN, Ruling SHEN. Application of Optimized Latex Perfusion Technique in the Establishment of Craniofacial Venous Model in Mice [J]. Laboratory Animal and Comparative Medicine, 2023, 43(5): 574-578. |
[11] | Lianxiang GUO. Revision of Standards for Microbiological and Parasitological Grades in Laboratory Animals and Its Comparison to Foreign Standards [J]. Laboratory Animal and Comparative Medicine, 2023, 43(4): 339-346. |
[12] | Ying HUANG, Siyu WEI, Li CAI, Sujing QIANG, Dongting LI, Yuqiang DING. Microbiological Monitoring Analysis of Laboratory Rats and Mice from Vendors: Department of Laboratory Animal Science of Fudan University as an Example [J]. Laboratory Animal and Comparative Medicine, 2023, 43(4): 347-354. |
[13] | Xinyan BIAN, Yong LU, Yan WANG, Qiang SUN. Analysis of the Birthing Behaviour of Cynomolgus Macaques [J]. Laboratory Animal and Comparative Medicine, 2023, 43(4): 355-362. |
[14] | Yasheng DENG, Jiang LIN, Chiling GAN, Guanfeng ZENG, Jiayin HUANG, Huifang DENG, Yingxian MA, Siyin HAN. Literature Analysis of the Preparation Elements of Animal Models of Skin Photoaging and the Data of Subjects [J]. Laboratory Animal and Comparative Medicine, 2023, 43(4): 406-414. |
[15] | Hui CHENG, Fei FANG, Jiahao SHI, Hua YANG, Mengjie ZHANG, Ping YANG, Jian FEI. H1 Linker Histone Gene Regulates Lifespan via Dietary Restriction Pathways in Caenorhabditis elegans [J]. Laboratory Animal and Comparative Medicine, 2023, 43(3): 271-281. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||