Abstract: Objective To investigate the nephron sparing surgery by regional occlusion with dogs. Methods By using the regional blocking renal blood tool developed by the authors, 5 healthy male Beagle dogs underwent nephron sparing surgery (NSS). While 3 healthy male Beagle dogs underwent NSS by blocking the renal artery. Results All the 8 Beagle dogs successfully underwent the surgery and had excellent recovery. All the outcome measures between two groups had no statistically significant differences. Conclusion Nephron sparing surgery by regional occlusion using our self-made tools is safe and effective. This method might be better able to protect renal function.

Key words: Regional occlusion, Nephron sparing surgery, Beagle dogs