外泌体通过NRF2/SLC7A11/GPX4通路调控铁死亡治疗小鼠缺血性脑卒中

徐英韬, 王蒙蒙, 林平, 迟海涛, 王怡, 白鹰

Exosomes Treat Ischemic Stroke by Regulation of Ferroptosis Through the NRF2/SLC7A11/GPX4 Pathway in Mice

XU Yingtao, WANG Mengmeng, LIN Ping, CHI Haitao, WANG Yi, BAI Ying

图1 外泌体的电镜观测和粒径分析 注：A，电镜观测下的外泌体直径约100 nm，呈球状（比例尺为100 nm）；B，外泌体悬液的粒径分析。

Figure 1 Electron microscopic observation and particle size analysis of exosomes Note： A， Exosome observed under electron microscopy has a diameter of approximately 100 nm and is spherical in shape （the scale bar is 100 nm）； B， Particle size analysis of exosome suspension.