登革病毒对树鼩不同组织来源细胞的易感性及感染特性研究
刘欣1, 杞梦迪1, 王文广1, 罕园园1, 陆美丽1,2, 李娜1, 代解杰1(), 陆彩霞1()()
Study on Susceptibility and Infection Characteristics of Dengue Virus in Cells Sourced from Different Tissues of Tree Shrews
LIU Xin1, QI Mengdi1, WANG Wenguang1, HAN Yuanyuan1, LU Meili1,2, LI Na1, DAI Jiejie1(), LU Caixia1()()

图3. 噬斑实验测定不同树鼩细胞中登革病毒的病毒滴度
注：A，C6/36细胞中DENV增殖所形成的斑块；B，TAECs中DENV增殖所形成的斑块；C，TASMCs中DENV增殖所形成的斑块；D，THs中DENV增殖所形成的斑块；E，pTRECs中DENV增殖所形成的斑块；F，TBMECs中DENV增殖所形成的斑块。C6/36细胞作为阳性对照；红圈指示噬斑；10-3、10-4、10-5表示病毒液稀释倍数；control表示未感染病毒的对照孔。

Figure 3. Quantification of dengue virus （DENV） titer in tree shrew cells of different tissues via plaque assay
Note： A， Plaques formed by DENV proliferating in C6/36 （positive control）； B， Plaques formed in tree shrew aortic endothelial cells （TAECs）； C， Plaques formed tree shrew aortic smooth muscle cells （TASMCs）； D， Plaques formed in tree shrew hepatocytes （THs）； E， Plaques formed by DENV proliferating in primary tree shrew renal epithelial cells （pTRECs）； F， Plaques in primary tree shrew brain microvascular endothelial cells （TBMECs）. The C6/36 cells were employed as the positive control. Red circles demarcate individual plaques. Viral dilutions are indicated as 10-3， 10-4， and 10-5. The “control” denotes uninfected wells， serving as a negative reference.