基于16S rRNA测序的2型糖尿病db/db小鼠模型口腔菌群差异分析

潘钱家, 葛峻沂, 胡楠, 华飞, 顾敏

Differential Analysis of Oral Microbiota in db/db Mouse Model of Type 2 Diabetes Utilizing 16S rRNA Sequencing

PAN Qianjia, GE Junyi, HU Nan, HUA Fei, GU Min

图3 db/db小鼠与db/m小鼠口腔微生物菌群在门水平上的差异 注：A～B，db/db组和db/m组口腔微生物在门水平上的群落组成直方图；C，变形杆菌门的相对丰度。db/db小鼠为糖尿病实验组；db/m小鼠为正常对照组，每组8只。*P＜0.05。

Figure 3 Comparison of oral microbiota between db/db mice and db/m mice at the phylum level Note：A-B， Phylum-level community composition of oral microbiota in db/db and db/m groups； C， Relative abundance of p_Proteobacteria. db/db mice served as the diabetic model， while db/m mice were the normal controls， n=8 per group. *P＜0.05.