基于16S rRNA测序的2型糖尿病db/db小鼠模型口腔菌群差异分析
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潘钱家, 葛峻沂, 胡楠, 华飞, 顾敏
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Differential Analysis of Oral Microbiota in db/db Mouse Model of Type 2 Diabetes Utilizing 16S rRNA Sequencing
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PAN Qianjia, GE Junyi, HU Nan, HUA Fei, GU Min
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图1 db/db小鼠及db/m小鼠的血糖相关指标差异 注:A,禁食12 h的空腹血糖(FBG)浓度;B,0~2 h的口服葡萄糖耐量(OGTT)分析;C,OGTT试验的曲线下面积(AUC)。db/db小鼠为糖尿病实验组;db/m小鼠为正常对照组,每组8只。*P<0.05,**P<0.01,***P<0.001。
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Figure 1 Comparison of blood glucose indices in db/db mice and db/m mice Note:A, The concentration of fasting blood glucose (FBG) levels after a 12-hour fasting period; B, Analysis of oral glucose tolerance test (OGTT) from 0-2 hours; C, Area under the curve (AUC) of the OGTT. Db/db mice served as the diabetic group, while db/m mice were the normal controls, n=8 per group. *P<0.05, **P<0.01, ***P<0.001.
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