来曲唑缓释片皮下给药构建小鼠多囊卵巢综合征模型及其肝脏转录组学分析

许秋雨, 严国锋, 付丽, 范文华, 周晶, 朱莲, 仇淑雯, 张洁, 吴铃

A Mouse Model of Polycystic Ovary Syndrome Established Through Subcutaneous Administration of Letrozole Sustained-Release Pellets and Hepatic Transcriptome Analysis

XU Qiuyu, YAN Guofeng, FU Li, FAN Wenhua, ZHOU Jing, ZHU Lian, QIU Shuwen, ZHANG Jie, WU Ling

图 4 来曲唑和高脂饮食造模后差异表达基因的GSEA 富集分析 注：A~B，来曲唑造模组 vs 安慰剂对照组GSEA富集分析（A，高表达基因集；B，低表达基因集）。FDR，假发现率。

Figure 4 GSEA enrichment analysis of differentially expressed genes after letrozole and high-fat diet modeling Note： A-B， GSEA enrichment analysis of genes in the letrozole model group compared to the placebo control group （A，upregulated gene sets； B， downregulated gene sets）. FDR， False discovery rate.