利用辅助生殖技术挽救基因修饰小鼠的实例分析

王芊芊(

), 陶斯珏, 卫振, 金晖晖, 刘平, 汪洌(

)(

)

A Case Study of Using Assisted Reproductive Technology to Rescue Genetically Modified Mice with Reproductive Disorder Phenotypes

WANG Qianqian(

), TAO Sijue, WEI Zhen, JIN Huihui, LIU Ping, WANG Lie(

)(

)

图3. 青年组与中老龄组受精率、异形卵率和仔鼠出生率的比较
注：A，青年组与中老年组小鼠体外受精后的受精率比较；B，青年组与中老年组小鼠体外受精后的异形卵率比较；C，青年组与中老年组小鼠体外受精-胚胎移植后的仔鼠出生率比较。^*P＜0.05，^***P＜0.001，ns，差异无统计学意义；D，雄性小鼠年龄与受精率的关系。

Figure 3. Comparison between the young group and the middle-aged and aged group in their fertility rates， abnormal egg rates， and birth rates
Note： A， Comparison of in vitro fertilization （IVF） fertilization rates between the young group and the middle-aged and aged group； B， Comparison of IVF abnormal egg rates between the young group and the middle-aged and aged group； C， Comparison of IVF-embryo transfer （ET） birth rate between the young group and the middle-aged and aged group. ^*P<0.05， ^***P<0.001； ns， differences were not statistically significant； D， Correlation between male mice age and fertility rate.