利用辅助生殖技术挽救基因修饰小鼠的实例分析
王芊芊(), 陶斯珏, 卫振, 金晖晖, 刘平, 汪洌()()
A Case Study of Using Assisted Reproductive Technology to Rescue Genetically Modified Mice with Reproductive Disorder Phenotypes
WANG Qianqian(), TAO Sijue, WEI Zhen, JIN Huihui, LIU Ping, WANG Lie()()

图1. 雄性小鼠采集精子团及获能1 h后的精子状态
注:A,采集的雄性小鼠一侧附睾尾与一段输精管;B,将附睾尾中采集的精子团放入精子获能液滴中;C,2只不同品系雄性小鼠的精子在获能1 h后的精子状态,左侧培养液滴中的精子稀薄,右侧培养液滴中精子散开均匀。

Figure 1. Sperm masses collected from male mice and sperm status after 1 h of capacitation
Note:A, The unilateral cauda epididymidis and a segment of the vas deferens from a male mouse; B, Sperm masses collected from the cauda epididymidis placed into droplets of sperm capacitation medium; C, The sperm status of two different strains of male mice after 1 h of capacitation: in the left culture droplet, the sperm were sparse, while in the right culture droplet, they were evenly dispersed.