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利用辅助生殖技术挽救基因修饰小鼠的实例分析
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王芊芊(  ), 陶斯珏, 卫振, 金晖晖, 刘平, 汪洌(  )(  )
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A Case Study of Using Assisted Reproductive Technology to Rescue Genetically Modified Mice with Reproductive Disorder Phenotypes
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WANG Qianqian(  ), TAO Sijue, WEI Zhen, JIN Huihui, LIU Ping, WANG Lie(  )(  )
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图1. 雄性小鼠采集精子团及获能1 h后的精子状态 注:A,采集的雄性小鼠一侧附睾尾与一段输精管;B,将附睾尾中采集的精子团放入精子获能液滴中;C,2只不同品系雄性小鼠的精子在获能1 h后的精子状态,左侧培养液滴中的精子稀薄,右侧培养液滴中精子散开均匀。
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Figure 1. Sperm masses collected from male mice and sperm status after 1 h of capacitation Note:A, The unilateral cauda epididymidis and a segment of the vas deferens from a male mouse; B, Sperm masses collected from the cauda epididymidis placed into droplets of sperm capacitation medium; C, The sperm status of two different strains of male mice after 1 h of capacitation: in the left culture droplet, the sperm were sparse, while in the right culture droplet, they were evenly dispersed.
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