肥胖食蟹猴一般身体指标、血糖、血脂的动态监测及相关性分析
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韦炎冶, 申果, 张鹏飞, 石松平, 胡家豪, 张绪哲, 花慧源, 花冠洋, 陆宏正, 曾勇, 季风, 韦祝梅
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Dynamic Monitoring and Correlation Analysis of General Body Indicators, Blood Glucose, and Blood Lipid in Obese Cynomolgus Monkeys
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WEI Yanye, SHEN Guo, ZHANG Pengfei, SHI Songping, HU Jiahao, ZHANG Xuzhe, HUA Huiyuan, HUA Guanyang, LU Hongzheng, ZENG Yong, JI Feng, WEI Zhumei
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表1 正常与肥胖食蟹猴各指标比较 (±s)
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Table 1 Comparison of various indicators between normal and obese cynomolgus monkeys
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指标 Indicator | 正常组(N=30) Normal group | 肥胖组(N=99) Obese group | F值 F value | P值 P value |
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| 2022 | 2023 | 2024 | 2022 | 2023 | 2024 | F交互a | F时间b | F组间c | P交互a | P时间b | P组间c |
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| AC l/cm | 37.12±4.27 | 38.13±5.14 | 36.93±6.42 | 46.58±7.35** | 50.03±8.47**△△ | 49.77±8.53**△△ | 3.487 | 5.969 | 67.589 | 0.032 | <0.01 | <0.01 | | SFT d/mm | 4.55±2.21 | 8.30±4.43△△ | 8.17±4.82△△ | 13.40±9.29** | 18.76±10.14**△△ | 22.01±12.82**△△ | 3.524 | 20.057 | 39.045 | 0.032 | <0.01 | <0.01 | | BW m/kg | 6.93±0.91 | 7.27±0.93 | 7.30±1.09 | 9.59±1.81** | 10.50±2.20**△△ | 10.60±2.20**△△ | 2.893 | 13.517 | 70.542 | 0.059 | <0.01 | <0.01 | | BMI | 33.13±3.45 | 34.20±4.67 | 34.51±5.81 | 42.88±6.10** | 47.17±8.25**△△ | 48.57±0.59**△△ | 4.433 | 12.116 | 77.520 | 0.014 | <0.01 | <0.01 | | TG c/(mmol·L-1) | 0.63±0.23 | 0.77±0.34 | 0.69±0.23 | 0.75±0.45 | 1.08±0.67*△△ | 0.98±0.49**△△ | 1.968 | 9.659 | 8.423 | 0.144 | <0.01 | 0.040 | | TC c/(mmol·L-1) | 1.86±0.41 | 2.26±0.42△△ | 2.09±0.52 | 2.07±0.44** | 2.47±0.55△△ | 2.10±0.45 | 4.480 | 53.847 | 2.704 | 0.012 | <0.01 | 0.103 | | LDL-C c/(mmol·L-1) | 0.97±0.25 | 0.84±0.27 | 0.81±0.30 | 0.96±0.29 | 0.95±0.36 | 0.88±0.31* | 1.902 | 6.624 | 1.271 | 0.151 | <0.01 | 0.262 | | HDL-C c/(mmol·L-1) | 1.69±0.60 | 2.23±0.69△△ | 2.29±0.69△△ | 2.07±0.67 | 2.26±0.77△ | 2.06±0.64 | 7.541 | 12.433 | 0.302 | 0.010 | <0.01 | 0.584 | | FPG c/(mmol·L-1) | 4.40±0.24 | 4.52±1.12 | 4.49±1.58 | 4.48±1.04 | 5.25±1.99△△ | 5.10±1.83△△ | 1.826 | 3.442 | 3.524 | 0.163 | 0.034 | 0.063 | | HbA1c ω/% | 4.12±1.34 | 4.11±0.29 | 4.10±0.25 | 4.21±0.19 | 4.42±0.92△ | 4.45±1.45 | 0.606 | 0.437 | 3.502 | 0.547 | 0.642 | 0.064 |
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