SHJH hr 小鼠的心脏衰老表型研究
刘荣乐1, 程灏1, 尚付生2, 常书福1()(), 徐平3
Study on Cardiac Aging Phenotypes of SHJH hr Mice
LIU Rongle1, CHENG Hao1, SHANG Fusheng2, CHANG Shufu1()(), XU Ping3

图1. 心脏超声检测不同周龄SHJH hr 小鼠的心脏功能
注:A,多普勒超声图;B~E,心功能指标的组间比较:每搏输出量(SV)、射血分数(EF)、 缩短分数(FS)和 二尖瓣前向血流e峰与a峰的比值(E'/A')。以非早衰的野生型ICR小鼠(WT组)作为对照,n=6;*P<0.05。

Figure 1. Cardiac ultrasound examination of SHJH hr mice cardiac function at different ages
Note: A, Doppler ultrasound images; B to E, Intergroup comparison of cardiac function indicators: stroke volume (SV), ejection fraction (EF), fractional shortening (FS), and the ratio of the early (E') to late (A') mitral inflow velocities (E'/A'). Wild-type ICR mice without premature aging (WT group) were used as controls, n=6; *P<0.05.