Laboratory Animal and Comparative Medicine ›› 2022, Vol. 42 ›› Issue (6): 566-571.DOI: 10.12300/j.issn.1674-5817.2022.077

• Laboratory Animal Welfare and Ethics • Previous Articles     Next Articles

A Brief Interpretation of CCAC Guide on Humane Endpoints of Animals: 2022 Edition

Xiaying LI1()(), Yusheng WEI1, Yonglu TIAN1, Wanyong PANG2()()   

  1. 1.Laboratory Research Center, School of Life Science, Peking University, Beijing 100871, China
    2.Translational In Vivo Model Research Platform, Sanofi G&D, Beijing 100022, China
  • Received:2022-06-08 Revised:2022-07-21 Online:2022-12-25 Published:2023-01-04
  • Contact: Wanyong PANG

Abstract:

The 2022 Canadian Council On Animal Care (CCAC) guidelines: Identification of Scientific Endpoints, Human Intervention Points, and Cumulative Endpoints (CCAC Guide) supplements existing laboratory animal humane endpoint theory according to the latest available literature. This article summarized the main content of the 2022 CCAC Guide, and elaborated and analyzed the determination, implementation and supervision of the scientific endpoints, humane intervention points, and cumulative endpoints of animal experiments, in order to provide useful reference and information.

Key words: Laboratory animals, Scientific endpoints, Humane intervention points, Cumulative end points

CLC Number: