实验动物与比较医学 ›› 2018, Vol. 38 ›› Issue (1): 54-56.DOI: 10.3969/j.issn.1674-5817.2018.01.010

所属专题: 实验动物资源开发与利用

• 论著 • 上一篇    下一篇

CMU/1和CMU/2长爪沙鼠繁殖性能与生长发育观测

李迎1,3, 杜小燕2, 崔晓霞1, 马兰芝1, 尚世臣1, 黄斌1, 赵权3, 李桂军1, 王冬平1, 陈振文2   

  1. 1.军事科学院军事医学研究院实验动物中心,北京 100071;
    2.首都医科大学实验动物科学部,北京 100069;
    3.吉林农业大学动物科学技术学院,长春 130118
  • 收稿日期:2017-08-05 出版日期:2018-02-25 发布日期:2021-03-01
  • 作者简介:李迎(1993-),女,硕士,研究方向:实验动物生物学特性研究。E-mail:651998038@qq.com
  • 基金资助:
    国家科技支撑计划课题(2015BAI09B01-04)

Preliminary Study on Growth and Reproductive Performance of Inbred Mongolian Gerbil Strains CMU/1 and CMU/2

LI Ying1,3, DU Xiao-yan2, CUI Xiao-xia1, MA Lan-zhi1, SHANG Shi-chen1, HUANG Bin1, ZHAO Quan3, LI Gui-jun1, WANG Dong-ping1, CHEN Zhen-wen2   

  1. 1. Laboratory Animal Center,Military Medical Sciences,Military Academy,Beijing 100071,China;
    2. Department of Laboratory Animal Science,Capital Medical University Sciences,Beijing 100069,China;
    3. College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China
  • Received:2017-08-05 Online:2018-02-25 Published:2021-03-01

摘要: 目的 探讨CMU/1和CMU/2长爪沙鼠生长繁殖性能,为其近交系应用、保种和生产繁殖提供基础数据。方法 选择F20~F22代种鼠,按照近交系动物配对方式进行繁育,观测统计1~5胎的胎间隔、窝产仔数、离乳数,生长发育等数据。结果 CMU/1和CMU/2初生体质量为2.5~3.4 g,窝产仔数最少1只, 最多9只, 离乳成活率为65%~75%, 胎间隔最短14 d, 最长171 d。2~6周龄体质量增长较快。结论 CMU/1及CMU/2长爪沙鼠窝产仔数差异显著,胎间隔大多数在21~70 d。两个品系长爪沙鼠繁殖性能无明显差异。

关键词: 长爪沙鼠, 近交系, 脑缺血模型, 生长与繁殖性能

Abstract: Objective To investigate the growth and reproductive performance of CMU/1 and CMU/2 ischemia-prone inbred gerbils;And to provide the data support for its’application,conservation and breeding.Methods The generations F20~F22 of 2 gerbil lines were selected and bred in accordance with inbreed Mating rule.The litter interval,the number of birth,the number of weaned pups and the growth curve of the 1~5 litters was analyzed.Results The birth weight of CMU/1 and CMU/2 was 2.5 g to 3.4 g.The litter size ranged from at least 1 to the most 9.The survival rate of weaned litter from 65% to 75%.The shortest litter interval was 14 days,whereas the longest 171 days.The weight gain at 2 to 6 week of age was more rapid.Conclusion There is significant difference in litter size between CMU/1 and CMU/2 ischemia-prone inbred gerbil.Most of them display birth intervals in the 21~70 day.Genotype seems have no effect on the reproductive characteristics of ischemia-prone inbred gerbils.

Key words: Gerbils, Inbred lines, Ischemia model, Growth and reproductive performance

中图分类号: