实验动物与比较医学 ›› 2021, Vol. 41 ›› Issue (3): 252-258.DOI: 10.12300/j.issn.1674-5817.2021.077

所属专题: 实验动物设施设备

• 实验动物设施与技术 • 上一篇    下一篇

两种不同类型实验动物屏障设施的气流组织计算流体力学模拟技术分析

周斌1, 赵勇2, 汪亚兵1, 刘吉宏1   

  1. 1.上海开纯洁净室技术工程有限公司,上海 201233;
    2.上海实验动物研究中心,上海201203
  • 收稿日期:2021-04-06 修回日期:2021-05-26 出版日期:2021-06-25 发布日期:2021-07-05
  • 作者简介:周 斌(1989—), 男, 硕士, 研究方向: 暖通设计。E-mail: 18817367393@163.com
  • 基金资助:
    上海市科学技术委员会科研计划项目: 实验动物设施与环境动态质量、运行能力的检测与评价(18140900600)

Analysis on Air Distribution by Computational Fluid Dynamics Simulation in Two Types of Laboratory Animal Barrier Facilities

ZHOU Bin1, ZHAO Yong2, WANG Yabing1, LIU Jihong1   

  1. 1. Shanghai Kaichun Clean-Room Technology Co. Ltd., Shanghai 201233, China;
    2. Shanghai Laboratory Animal Research Center, Shanghai 201203, China
  • Received:2021-04-06 Revised:2021-05-26 Online:2021-06-25 Published:2021-07-05

摘要: 选取动物实验和生产两种不同类型屏障设施作为研究对象,以余热排除效率、氨气排污效率、二氧化碳排污效率以及平均空气龄作为其气流组织的评价指标。采用计算流体力学(computational fluid dynamics,CFD)数值模拟技术,对比分析了在不同换气次数、不同排风口位置情况下,两种类型实验动物设施的气流组织优劣势。结果表明,以上述指标评价时,顶部送风、下侧排风辅助的送排风形式较为适合。此外,对于饲养密度高的实验动物生产设施,建议根据饲养室的热负荷程度调整最低换气次数。

关键词: 动物实验, 动物生产, 屏障设施, 排污效率, 平均空气龄, 气流组织

Abstract: Taking the removal efficiencies of waste heat, ammonia, and carbon dioxide, and the mean age of air as the evaluation indicators of air distribution, the pros and cons of air distribution in two different types of animal barriers, an experimental facility and a breeding facility, were analyzed at various air change rates and exhaust outlet positions by computational fluid dynamics (CFD) numerical simulation technology. The results of selected indicators showed that ceiling air supply plus bottom exhaust outlet were suitable for the laboratory animal barrier facilities. In addition, air change rate in high-density breeding facilities should be adjusted according to the room temperature.

Key words: Animal experiment, Animal breeding, Barrier facility, Removal efficiency, Mean age of air

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